Anti-HIVEP1 antibody [2417C2 a] (ab58652)

Overview

  • Product nameAnti-HIVEP1 antibody [2417C2 a]
    See all HIVEP1 primary antibodies
  • Description
    Mouse monoclonal [2417C2 a] to HIVEP1
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant C terminal fragment of human HIVEP1

Properties

Applications

Our Abpromise guarantee covers the use of ab58652 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 297 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionThis protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
  • Sequence similaritiesContains 5 C2H2-type zinc fingers.
  • DomainContains two sets of 2 zinc-fingers, which are widely separated and recognize the same DNA sequence. There is a fifth zinc-finger in-between.
  • Cellular localizationCytoplasm. Nucleus and Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cirhin interaction protein antibody
    • CIRIP antibody
    • CRYBP1 antibody
    • GAAP antibody
    • Gate keeper of apoptosis-activating protein antibody
    • HIV EP1 antibody
    • HIV-EP1 antibody
    • HIVEP 1 antibody
    • Hivep1 antibody
    • Human immunodeficiency virus type I enhancer binding protein 1 antibody
    • Human immunodeficiency virus type I enhancer-binding protein 1 antibody
    • Major histocompatibility complex binding protein 1 antibody
    • Major histocompatibility complex-binding protein 1 antibody
    • MBP 1 antibody
    • MBP-1 antibody
    • Positive regulatory domain II binding factor 1 antibody
    • Positive regulatory domain II-binding factor 1 antibody
    • PRDII BF1 antibody
    • PRDII-BF1 antibody
    • Schnurri 1 antibody
    • ZAS1 antibody
    • ZEP1_HUMAN antibody
    • Zinc finger protein 40 antibody
    • ZNF40 antibody
    • ZNF40A antibody
    see all

Anti-HIVEP1 antibody [2417C2 a] images

References for Anti-HIVEP1 antibody [2417C2 a] (ab58652)

ab58652 has not yet been referenced specifically in any publications.

Product Wall

Gracias por tu respuesta, y por enviar las imágenes.

Dado que en nuestro laboratorio no se ha testado el anticuerpo con la proteína endógena, me temo que no tengo evidencias para asegurar que la banda a 34KDa corresponde ...

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Gracias por contactarnos.

Espero que no te importe que te conteste en castellano, ya que recientemente hemos inaugurado el Servicio Técnico en español. Si prefirieses seguir contactándonos en inglés, no dudes en co...

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Thank you very much for your interest in ab58652. To our knowledge, ab58652 has not been tested in immunohistochemistry on paraffin-embedded sections (IHC-P) yet. However, we do not see a reason why it should not work. Therefore, I can offer a disco...

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Thank you for contacting us. The immunogen is a C-terminal fragment within residues 2550 and the C-terminus of isoform 1 - based on the UniProt database entry for the human protein P15822. http://www.uniprot.org/uniprot/P15822 The exact epitope ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"