Overview

  • Product name
    Anti-HLA B27 antibody [EP-4]
    See all HLA B27 primary antibodies
  • Description
    Mouse monoclonal [EP-4] to HLA B27
  • Tested applications
    Suitable for: ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation. Lymphocytes from HLA-B27 individual.

  • Positive control
    • Blood
  • General notes


    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Purified IgM
  • Primary antibody notes
    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.
  • Clonality
    Monoclonal
  • Clone number
    EP-4
  • Isotype
    IgM
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.

For use with paraformaldehyde fixed cell suspensions or cytospins.

Target

  • Relevance
    Involved in the presentation of foreign antigens to the immune system. HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells.
  • Cellular localization
    Single-pass type 1 membrane protein
  • Database links
  • Alternative names
    • HLAB antibody
    • Leukocyte antigen class I B antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex class I B antibody
    • SPDA1 antibody
    see all

References for Anti-HLA B27 antibody [EP-4] (ab24094)

ab24094 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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