Overview

  • Product nameAnti-HLA C antibody
    See all HLA C primary antibodies
  • Description
    Rabbit polyclonal to HLA C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 208-257 (PPKTHVTHHP LSDHEATLRC WALGFYPAEI TLTWQRDGED QTQDTELVET) of Human HLA C (NP_002108).

  • Positive control
    • MDA-MB-435S cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 41 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionInvolved in the presentation of foreign antigens to the immune system.
  • Sequence similaritiesBelongs to the MHC class I family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Post-translational
    modifications
    Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1C07_HUMAN antibody
    • Cw-7 alpha chain antibody
    • D6S204 antibody
    • HLA class I histocompatibility antigen antibody
    • HLA class I histocompatibility antigen, C alpha chain antibody
    • HLA class I histocompatibility antigen, Cw-1 alpha chain antibody
    • HLA JY3 antibody
    • HLA-C antibody
    • HLC C antibody
    • Human leukocyte antigen C alpha chain antibody
    • Major histocompatibility antigen HLA C antibody
    • Major histocompatibility complex, class I, C antibody
    • MHC class I antigen Cw*7 antibody
    • MHC class I antigen heavy chain HLA C antibody
    • PSORS1 antibody
    see all

Anti-HLA C antibody images

  • Anti-HLA C antibody (ab125395) at 1 µg/ml + MDA-MB-435S cell lysate at 10 µg with milk at 5 %

    Predicted band size : 41 kDa

References for Anti-HLA C antibody (ab125395)

ab125395 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"