Anti-HLA Class 1 A1, A11, A26 antibody [8.L.101] (ab33883)

Overview

  • Product name
    Anti-HLA Class 1 A1, A11, A26 antibody [8.L.101]
  • Description
    Mouse monoclonal [8.L.101] to HLA Class 1 A1, A11, A26
  • Specificity
    This antibody reacts to HLA Class 1 A1, A11, A26. Additional crossreactivity occurs with related proteins. Specificity was determined at a 1/10 dilution by the microcytotoxicity test under standard conditions.
  • Tested applications
    Suitable for: Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    HLA Class 1 Antigen A1, A11, A26.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: Ascites
  • Concentration information loading...
  • Purity
    Ascites
  • Clonality
    Monoclonal
  • Clone number
    8.L.101
  • Isotype
    IgM
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab33883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. ab91545-Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.
This antibody is also suitable for use in Cytotoxicity, Cell Typing and Chimerism Studies.

Target

  • Relevance
    HLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa.
  • Cellular localization
    Membrane; single pass type I membrane protein.
  • Database links
  • Alternative names
    • Histocompatibility type A antibody
    • HLA A antibody
    • HLA class I antigen antibody
    • HLA class I heavy chain antibody
    • HLA class I molecule antibody
    • HLAA antibody
    • Major histocompatibility complex class I A antibody
    see all

References

ab33883 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

The antibody is presented as crude ascites, with no purification. As is the case for most ascites preparations, the immunoglobulin concentration is not determined. Ascites generally contains 1 - 10 mg/ml total antibody, of which 90% is specific for the...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up