Anti-HLA class I A, B, C antibody (ab126237)

Overview

  • Product name
    Anti-HLA class I A, B, C antibody
  • Description
    Rabbit polyclonal to HLA class I A, B, C
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1 and 206 of Human HLA class I A, B, C (AAH03069).

  • Positive control
    • A549 whole cell lysate; HepG2 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78% PBS, 20% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab126237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.

Target

  • Function
    Involved in the presentation of foreign antigens to the immune system.
  • Sequence similarities
    Belongs to the MHC class I family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Post-translational
    modifications
    Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1A03_HUMAN antibody
    • A-1 alpha chain antibody
    • A-3 alpha chain antibody
    • antigen presenting molecule antibody
    • AS antibody
    • D6S204 antibody
    • HLA class I histocompatibility antigen antibody
    • HLA-A antibody
    • HLA-A heavy chain antibody
    • HLA-JY3 antibody
    • HLAA antibody
    • HLAB antibody
    • HLC-C antibody
    • leukocyte antigen class I-A antibody
    • MHC class I antigen antibody
    • MHC class I antigen A*3 antibody
    • PSORS1 antibody
    • SPDA1 antibody
    see all

Images

  • Anti-HLA class I A, B, C antibody (ab126237) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 41 kDa



    10% SDS PAGE

References

ab126237 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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