Anti-HLA Class II DR4 antibody [8.L.335] (ab33903)


  • Product nameAnti-HLA Class II DR4 antibody [8.L.335]
    See all HLA Class II DR4 primary antibodies
  • Description
    Mouse monoclonal [8.L.335] to HLA Class II DR4
  • SpecificityThis antibody reacts to HLA Class II DR4. It also crossreacts with the related proteins DR15 and DQ1. Specificity was determined at a 1/10 dilution by the microcytotoxicity test under standard conditions.
  • Tested applicationsSuitable for: Microcytotoxicity testing, Flow Cyt, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein (Human)

  • General notes

    This antibody has been used for Cell typing and Chimerism studies.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: Ascites
  • Concentration information loading...
  • PurityAscites
  • Primary antibody notesThis antibody has been used for Cell typing and Chimerism studies.
  • ClonalityMonoclonal
  • Clone number8.L.335
  • IsotypeIgM
  • Research areas


Our Abpromise guarantee covers the use of ab33903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Microcytotoxicity testing Use at an assay dependent concentration.

Add 0.9ml of 1% BSA in PBS to 100µl of X10 antibody stock.

Flow Cyt Use at an assay dependent concentration. ab91545-Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody.
ICC Use at an assay dependent concentration.


  • RelevanceHLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
  • Cellular localizationMembrane; single pass type I membrane protein.
  • Database links
  • Alternative names
    • HLA DR4 antibody
    • HLA DRA antibody
    • HLA DRB antibody
    • HLADR4 antibody
    • Major histocompatibility complex class II DR4 antibody
    • MHC class II antigen DR antibody
    see all

References for Anti-HLA Class II DR4 antibody [8.L.335] (ab33903)

ab33903 has not yet been referenced specifically in any publications.

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Thank you for your enquiry. It also crossreacts with the related proteins DR15 and DQ1. I have added this information to the datasheet. Thank you for bringing this to my attention. Please contact us again if you have further questions.