Overview

  • Product nameAnti-HLA DM antibody
    See all HLA DM primary antibodies
  • Description
    Rabbit polyclonal to HLA DM
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 58-107 (GLSEAYDEDQ LFFFDFSQNT RVPRLPEFAD WAQEQGDAPA ILFDKEFCEW) of Human HLA DM (NP_006111).

  • Positive control
    • MCF7 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab113870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceHuman Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.
  • Cellular localizationLate endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: Localizes to late endocytic compartment. Associates with lysosome membranes.
  • Database links
  • Alternative names
    • Class II histocompatibility antigen M alpha chain antibody
    • D6S222E antibody
    • DMA antibody
    • HLA class II histocompatibility antigen DM alpha chain antibody
    • HLA DMA antibody
    • HLADM antibody
    • Major histocompatibility complex class II DM alpha antibody
    • MHC class II antigen DMA antibody
    • OTTHUMP00000029242 antibody
    • OTTHUMP00000062997 antibody
    • OTTHUMP00000178727 antibody
    • OTTHUMP00000178728 antibody
    • OTTHUMP00000178729 antibody
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    • Ring 6 antibody
    • Ring6 antibody
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Anti-HLA DM antibody images

  • Anti-HLA DM antibody (ab113870) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Predicted band size : 29 kDa

References for Anti-HLA DM antibody (ab113870)

ab113870 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113870.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"