Overview

  • Product nameAnti-HLA DM antibody
    See all HLA DM primary antibodies
  • Description
    Mouse monoclonal to HLA DM
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-262 of Human HLA DM

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab55149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceHuman Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.
    • Cellular localizationLate endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: Localizes to late endocytic compartment. Associates with lysosome membranes.
    • Database links
    • Alternative names
      • Class II histocompatibility antigen M alpha chain antibody
      • D6S222E antibody
      • DMA antibody
      • HLA class II histocompatibility antigen DM alpha chain antibody
      • HLA DMA antibody
      • HLADM antibody
      • Major histocompatibility complex class II DM alpha antibody
      • MHC class II antigen DMA antibody
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    Anti-HLA DM antibody images

    • HLA DM antibody (ab55149) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human malignant lymphoma, diffuse large B tissue.


    • Predicted band size : 29 kDa
      HLA DM antibody (ab55149) at 1ug/lane + U-2 cell lysate at 25ug/lane.

    References for Anti-HLA DM antibody (ab55149)

    ab55149 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab55149.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"