• Product nameAnti-HLA DMB antibody
    See all HLA DMB primary antibodies
  • Description
    Rabbit polyclonal to HLA DMB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 40-89 (FTYCISFNKD LLTCWDPEEN KMAPCEFGVL NSLANVLSQH LNQKDTLMQR) of Human HLA DMB (NP_002109).


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab125387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • RelevanceHLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
  • Cellular localizationLate endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
  • Database links
  • Alternative names
    • class II antigen HLA-DM beta chain antibody
    • class II histocompatibility antigen antibody
    • Class II histocompatibility antigen M beta chain antibody
    • D6S221E antibody
    • DMB antibody
    • HLA class II histocompatibility antigen DM beta chain antibody
    • HLA-DM histocompatibility type, beta chain antibody
    • M beta chain antibody
    • Major histocompatibility complex class II DM beta antibody
    • MHC class II antigen DMB antibody
    • MHC class II antigen HLA DM beta chain antibody
    • MHC class II HLA DMB antibody
    • OTTHUMP00000029257 antibody
    • Really interesting new gene 7 protein antibody
    • RING 7 antibody
    • RING7 antibody
    see all

Anti-HLA DMB antibody images

  • Anti-HLA DMB antibody (ab125387) at 1 µg/ml + Human placenta

    Predicted band size : 29 kDa

References for Anti-HLA DMB antibody (ab125387)

ab125387 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125387.
Please use the links above to contact us or submit feedback about this product.