Anti-HLA-DOA antibody - N-terminal (ab180071)

Overview

  • Product name
    Anti-HLA-DOA antibody - N-terminal
    See all HLA-DOA primary antibodies
  • Description
    Rabbit polyclonal to HLA-DOA - N-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human HLA-DOA aa 31-59 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P06340

  • Positive control
    • HL-60 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab180071 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab180071 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 28 kDa.

Target

  • Relevance
    HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
  • Cellular localization
    Cell Membrane; Single-pass type I membrane protein.
  • Database links
  • Alternative names
    • HLA class II histocompatibility antigen, DO alpha chain precursor antibody
    • HLA D0 alpha antibody
    • HLA DNA antibody
    • HLA DZA antibody
    • HLADZ antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex, class II, DN alpha antibody
    • Major histocompatibility complex, class II, DO alpha antibody
    • MHC class II antigen DOA antibody
    • MHC DN alpha antibody
    • MHC DZ alpha antibody
    see all

Images

  • Anti-HLA-DOA antibody - N-terminal (ab180071) at 1/1000 dilution + HL-60 cell line lysates at 35 µg

    Predicted band size : 28 kDa

References

ab180071 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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