Anti-HLA DR + HLA DP antibody [HL-38], prediluted (FITC) (ab18232)

Overview

  • Product nameAnti-HLA DR + HLA DP antibody [HL-38], prediluted (FITC)
    See all HLA DR + HLA DP primary antibodies
  • Description
    Mouse monoclonal [HL-38] to HLA DR + HLA DP, prediluted (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Pig
  • Immunogen

    Burkitts lymphoma cell line Raji (Human).

  • EpitopeThis antibody recognizes a common epitope on the beta chain of human HLA DR and HLA DP.

Properties

Applications

Our Abpromise guarantee covers the use of ab18232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 20 µl of reagent per 100 µl of whole blood.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceHuman MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • Cellular localizationCell Membrane; Single pass type I membrane protein
    • Database links
    • Alternative names
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    References for Anti-HLA DR + HLA DP antibody [HL-38], prediluted (FITC) (ab18232)

    ab18232 has not yet been referenced specifically in any publications.

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