Overview

  • Product nameAnti-HLA DRw52 antibody [7.3.19.1], prediluted
  • Description
    Mouse monoclonal [7.3.19.1] to HLA DRw52, prediluted
  • SpecificityThe antibody reacts with a polymorphic determinant on HLA-DR molecules which is associated with DR3, DR5, and DRw6 (DRw52-like). It does not react with DRw8. The antibody reacts with part of the HLA-D molecules (29+34 kD). The determinant is strongly expressed on DR3 positive cells and more weakly on DR5 and DRw6 positive cells.
  • Tested applicationsSuitable for: ICC/IF, Microcytotoxicity testingmore details
  • Species reactivity
    Reacts with: Human, Chimpanzee, Macaque Monkey, Gorilla
  • General notes


    The antibody is useful for HLA-DR typing and biochemical characterization of the DR52w positive molecules and functional studies

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituent: 0.1% BSA
  • Concentration information loading...
  • PurityAscites
  • Primary antibody notesThe antibody is useful for HLA-DR typing and biochemical characterization of the DR52w positive molecules and functional studies
  • ClonalityMonoclonal
  • Clone number7.3.19.1
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab8142 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/10.

Dilution in PBS plus 1% BSA and 0.01% sodium azide is advised.

Microcytotoxicity testing 1/10.

Dilution in PBS plus 1% BSA and 0.01% sodium azide is advised.

References for Anti-HLA DRw52 antibody [7.3.19.1], prediluted (ab8142)

This product has been referenced in:
  • Bontrop RE  et al. Major histocompatibility complex class II-restricted antigen presentation across a species barrier: conservation of restriction determinants in evolution. J Exp Med 172:53-9 (1990). Read more (PubMed: 1694228) »
  • Koning F  et al. A mouse monoclonal antibody detecting a DR-related MT2-like specificity: serology and biochemistry. Hum Immunol 9:221-30 (1984). Read more (PubMed: 6232245) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"