Overview

  • Product name
    Anti-HLADQA1 + HLADQA2 antibody
  • Description
    Goat polyclonal to HLADQA1 + HLADQA2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Cynomolgus monkey
  • Immunogen

    Synthetic peptide:

    C-QGLRSVGASRH

    , corresponding to C terminal amino acids 241-251 of Human HLADQA1 + HLADQA2 (NP_064440.1; NP_002113.2).

  • Positive control
    • Human bone marrow lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106833 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 28 kDa.

Target

  • Relevance
    HLADQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). HLADQA2 forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site.
  • Cellular localization
    Endoplasmic reticulum, Golgi Apparatus and Plasma membrane
  • Database links
  • Alternative names
    • CD antibody
    • CELIAC1 antibody
    • DC-1 alpha antibody
    • DC-1 alpha chain antibody
    • DQ-A1 antibody
    • DX alpha chain antibody
    • DX-ALPHA antibody
    • FLJ27088 antibody
    • FLJ27328 antibody
    • GSE antibody
    • HLA class II histocompatibility antigen, DQ alpha 1 chain antibody
    • HLA class II histocompatibility antigen, DQ alpha 2 chain antibody
    • HLA class II histocompatibility antigen, DQ(6) alpha chain antibody
    • HLA class II histocompatibility antigen, DQ(W3) alpha chain antibody
    • HLA-DCA antibody
    • HLA-DQA antibody
    • HLA-DQA2 antibody
    • HLA-DXA antibody
    • leucocyte antigen DQA1 antibody
    • leukocyte antigen alpha chain antibody
    • major histocompatibility complex, class II, DQ alpha 1 antibody
    • major histocompatibility complex, class II, DQ alpha 2 antibody
    • MGC149527 antibody
    • MHC class II antigen antibody
    • MHC class II DQA1 antibody
    • MHC class II DQA2 antibody
    • MHC class II HLA-D alpha glycoprotein antibody
    • MHC class II HLA-DQ-alpha-1 antibody
    • MHC class II surface glycoprotein antibody
    • MHC HLA-DQ alpha antibody
    see all

Images

  • Anti-HLADQA1 + HLADQA2 antibody (ab106833) at 1 µg/ml + Human bone marrow lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 28 kDa
    Observed band size : 28 kDa


    Exposure time : 1 hour

References

ab106833 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab106833.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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