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Rabbit monoclonal [EPR14760] to HLTF
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human HLTF aa 1-100. The exact sequence is proprietary.
Database link: Q14527
Jurkat, Hela cell lysates, Hela cells
This product is a recombinant rabbit monoclonal antibody.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
Concentration information loading...
Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/2000. Predicted molecular weight: 113 kDa.
Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Protein modification; protein ubiquitination.
Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 RING-type zinc finger.
Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nuclear localization is stimulated by progesterone.
Information by UniProt
DNA-binding protein/plasminogen activator inhibitor 1 regulator antibody
Helicase like transcription factor antibody
Helicase-like transcription factor antibody
Western blot - Anti-HLTF [EPR14760] antibody (ab188567)
All lanes : Anti-HLTF antibody [EPR14760] (ab188567) at 1/2000 dilution Lane 1 : Hela cell lysate Lane 2 : Jurkat cell lysate Lysates/proteins at 10 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution Predicted band size : 113 kDa
Immunocytochemistry/ Immunofluorescence - Anti-HLTF [EPR14760] antibody (ab188567)
Immunocytochemical analysis of Hela cells fixed in 4% paraformaldehyde labeling HLTF with ab188567 at 1/100 dilution and Goat anti rabbit IgG(Alexa Fluor® 488) at 1/200 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"