Overview

  • Product name
    Anti-HMBOX1 antibody
  • Description
    Rabbit polyclonal to HMBOX1
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Zebrafish
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 142-377 of Human HMBOX1 (NP_078843)

  • Positive control

Properties

Applications

Our Abpromise guarantee covers the use of ab97643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

Target

  • Function
    Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor.
  • Tissue specificity
    Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, and colon.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization
    Nucleus. Cytoplasm. Predominantly detected in cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ21616 antibody
    • HMBOX1 antibody
    • HMBOX1A antibody
    • HMBX1_HUMAN antibody
    • HNF1LA antibody
    • homeobox containing 1 antibody
    • Homeobox containing protein 1 antibody
    • Homeobox-containing protein 1 antibody
    • homeobox-containing protein PBHNF antibody
    • PBHNF antibody
    see all

Images

  • Anti-HMBOX1 antibody (ab97643) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 47 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ab97643 at 1/200 dilution. Lower image is merged with DNA probe.
  • Immunohistochemical analysis of paraffin-embedded SW480 xenograft using ab97643 at 1/500 dilution.

References

This product has been referenced in:
  • Gong J  et al. miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. Cancer Sci 103:645-52 (2012). WB ; Human . Read more (PubMed: 22320217) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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