• Product nameAnti-HMGN3 antibody
    See all HMGN3 primary antibodies
  • Description
    Rabbit polyclonal to HMGN3
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat
  • Immunogen

    Synthetic peptide corresponding to a region between residue 60 and 99 of human HMGN3 (NP_004233.1)

  • Positive control
    • human Breast, Prostate adenocarcinoma.



Our Abpromise guarantee covers the use of ab84465 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
    • Tissue specificityExpressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries.
    • Sequence similaritiesBelongs to the HMGN family.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp686E20226 antibody
      • FLJ42187 antibody
      • High mobility group nucleosomal binding domain 3 antibody
      • High mobility group nucleosome-binding domain-containing protein 3 antibody
      • HMGN3 antibody
      • HMGN3_HUMAN antibody
      • OTTHUMP00000016772 antibody
      • OTTHUMP00000016773 antibody
      • PNAS 24 antibody
      • PNAS 25 antibody
      • PNAS24 antibody
      • PNAS25 antibody
      • Thyroid hormone receptor interacting protein 7 antibody
      • Thyroid receptor-interacting protein 7 antibody
      • TR-interacting protein 7 antibody
      • TRIP 7 antibody
      • TRIP-7 antibody
      • TRIP7 antibody
      see all

    Anti-HMGN3 antibody images

    • Detection of Human HMGN3 by ab84465 at 1:500 dilution using a Formalin-Fixed Paraffin-Embedded section of human breast. Detection by means of DAB staining.
    • Detection of Human HMGN3 by ab84465 at 1:500 dilution using a Formalin-Fixed Paraffin-Embedded section of human prostate adenocarcinoma. Detection by means of DAB staining.

    References for Anti-HMGN3 antibody (ab84465)

    ab84465 has not yet been referenced specifically in any publications.

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