Anti-hnRNP A1 (isoform A1-A) antibody (ab123378)

Overview

  • Product nameAnti-hnRNP A1 (isoform A1-A) antibody
  • Description
    Rabbit polyclonal to hnRNP A1 (isoform A1-A)
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    SSSQR

    , corresponding to a region around amino acids 190-194 of Human hnRNP A1 (isoform A1-A) (P09651).

  • Positive control
    • 293 cell extract

Properties

Applications

Our Abpromise guarantee covers the use of ab123378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 34, 39 kDa (predicted molecular weight: 39 kDa). Incubate membrane with diluted antibody in 5% nonfat milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking over night.

Target

  • FunctionInvolved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
  • Sequence similaritiesContains 2 RRM (RNA recognition motif) domains.
  • Post-translational
    modifications
    Arg-194, Arg-206 and Arg-225 are dimethylated, probably to asymmetric dimethylarginine.
    Sumoylated.
  • Cellular localizationNucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • Helix-destabilizing protein antibody
    • Heterogeneous nuclear ribonucleoprotein A1 antibody
    • HN RPA1L3 antibody
    • hnRNP A1 antibody
    • hnRNP core protein A1 antibody
    • HNRNPA1 antibody
    • M MGC102835 antibody
    • ROA1_HUMAN antibody
    • Single-strand RNA-binding protein antibody
    see all

Anti-hnRNP A1 (isoform A1-A) antibody images

  • Anti-hnRNP A1 (isoform A1-A) antibody (ab123378) at 1/500 dilution + 293 cell extract

    Predicted band size : 39 kDa

References for Anti-hnRNP A1 (isoform A1-A) antibody (ab123378)

ab123378 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123378.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"