• Product nameAnti-hnRNP L antibody
    See all hnRNP L primary antibodies
  • Description
    Rabbit polyclonal to hnRNP L
  • Tested applicationsSuitable for: ELISA, ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide from N terminal of human hnRNP L.

  • Positive control
    • Human colon carcinoma tissue, HeLa, Jurkat and HUVEC cell extracts and HeLa cells.



Our Abpromise guarantee covers the use of ab65049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.
IHC-P 1/50 - 1/100.
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).


  • FunctionThis protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.
  • Sequence similaritiesContains 3 RRM (RNA recognition motif) domains.
  • Post-translational
    Several isoelectric forms of the L protein are probably the results of post-translational modifications.
  • Cellular localizationNucleus > nucleoplasm. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • Database links
  • Alternative names
    • D830027H13Rik antibody
    • FLJ35509 antibody
    • Heterogeneous nuclear ribonucleoprotein L antibody
    • hnRNP L antibody
    • hnRNP-L antibody
    • Hnrnpl antibody
    • hnRPL antibody
    • HNRPL_HUMAN antibody
    • P/OKcl.14 antibody
    see all

Anti-hnRNP L antibody images

  • ab65049 at 1/500 dilution staining hnRNP L in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.
  • ab65049 at 1/50 dilution staining hnRNP L in human colon carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-hnRNP L antibody (ab65049) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : Jurkat cell extract
    Lane 3 : HUVEC cell extract
    Lane 4 : HUVEC cell extract with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 60 kDa
    Observed band size : 60 kDa

References for Anti-hnRNP L antibody (ab65049)

This product has been referenced in:
  • Roda D  et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS One 10:e0130543 (2015). Human . Read more (PubMed: 26110767) »
  • Li J  et al. HnRNPL as a key factor in spermatogenesis: Lesson from functional proteomic studies of azoospermia patients with sertoli cell only syndrome. J Proteomics : (2012). WB ; Human . Read more (PubMed: 22245417) »

See all 4 Publications for this product

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