Overview

  • Product nameAnti-hnRNP M1-M4 antibody
    See all hnRNP M1-M4 primary antibodies
  • Description
    Rabbit polyclonal to hnRNP M1-M4
  • Tested applicationsSuitable for: ELISA, WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from the N-terminal region of human hnRNP M1-M4.

  • Positive control
    • WB: extracts from HT29 cells; IHC-P: human breast carcinoma tissue; ICC/IF: MCF7 cells.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab73888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Predicted molecular weight: 78 kDa.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.

Target

  • FunctionPre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
  • Sequence similaritiesContains 3 RRM (RNA recognition motif) domains.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localizationNucleus > nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CEA receptor antibody
    • CEAR antibody
    • DKFZp547H118 antibody
    • Heterogeneous nuclear ribonucleoprotein M antibody
    • Heterogeneous nuclear ribonucleoprotein M4 antibody
    • Heterogenous nuclear ribonucleoprotein M4 antibody
    • hnRNA binding protein M4 antibody
    • hnRNP M antibody
    • Hnrnpm antibody
    • HNRNPM4 antibody
    • HNRPM antibody
    • HNRPM_HUMAN antibody
    • HNRPM4 antibody
    • HTGR1 antibody
    • N acetylglucosamine receptor 1 antibody
    • NAGR1 antibody
    see all

Anti-hnRNP M1-M4 antibody images

  • All lanes : Anti-hnRNP M1-M4 antibody (ab73888) at 1/500 dilution

    Lane 1 : extracts from HT29 cells
    Lane 2 : extracts from HT29 cells with immunizing peptide at 5 µg

    Lysates/proteins at 20 µg per lane.


    Predicted band size : 78 kDa
    Observed band size : 85 kDa (why is the actual band size different from the predicted?)
  • Left: immunofluorescence analysis of MCF7 cells, using 1/500-1/1000 ab73888; Right: same after pre-incubation with the immunizing peptide.
  • Left: immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using 1/50-1/100 ab73888; Right: same, after per-incubation with the immunizing peptide.

References for Anti-hnRNP M1-M4 antibody (ab73888)

ab73888 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"