Overview

  • Product name
  • Description
    Rabbit polyclonal to hnRNP M3-M4
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-180 of Human hnRNP M3-M4 (P52272).

  • Positive control
    • Human colon carcinoma tissue; HeLa cells; 293T and HeLa whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 77 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
  • Sequence similarities
    Contains 3 RRM (RNA recognition motif) domains.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localization
    Nucleus, nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CEA receptor antibody
    • CEAR antibody
    • Heterogeneous nuclear ribonucleoprotein M antibody
    • Heterogenous nuclear ribonucleoprotein M4 antibody
    • hnRNA binding protein M4 antibody
    • hnRNP M antibody
    • Hnrnpm antibody
    • HNRNPM4 antibody
    • HNRPM antibody
    • HNRPM_HUMAN antibody
    • HNRPM4 antibody
    • HTGR1 antibody
    • M3 antibody
    • M4 antibody
    • M4 protein antibody
    • N-acetylglucosamine receptor 1 antibody
    • NAGR1 antibody
    see all

Images

  • All lanes : Anti-hnRNP M3-M4 antibody (ab126103) at 1/10000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 77 kDa
  • ab126103, at 1/500 dilution, staining hnRNP M3-M4 in paraformaldehyde-fixed HeLa cells by Immunofluorescence (green). Alpha-tubulin filaments are stained in red and nuclei in blue.
  • ab126103, at 1/500 dilution, staining hnRNP M3-M4 in paraffin-embedded Human colon carcinoma tissue by Immunohistochemistry.

References

ab126103 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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