Anti-HOXC10 antibody (ab153904)
Key features and details
- Rabbit polyclonal to HOXC10
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-HOXC10 antibody
See all HOXC10 primary antibodies -
Description
Rabbit polyclonal to HOXC10 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment corresponding to Human HOXC10 aa 16-312.
Database link: Q9NYD6 -
Positive control
- HeLa, HepG2, Mouse muscle whole cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153904 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 38 kDa.
|
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IHC-P | (1) |
1/100 - 1/1000.
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ICC/IF | (1) |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 38 kDa. |
IHC-P
1/100 - 1/1000. |
ICC/IF
1/100 - 1/1000. |
Target
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Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
Sequence similarities
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 3226 Human
- Entrez Gene: 209448 Mouse
- Omim: 605560 Human
- SwissProt: Q9NYD6 Human
- SwissProt: P31257 Mouse
- Unigene: 44276 Human
- Unigene: 31665 Mouse
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Alternative names
- Hmeobox protein Hox C10 antibody
- Homeobox Protein Hox C10 antibody
- Homeobox protein Hox-3I antibody
see all
Images
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Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling HOXC10 with ab153904 at 1/2000 dilution. Alpha tubulin filaments were labeled red.
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All lanes : Anti-HOXC10 antibody (ab153904) at 1/1000 dilution
Lane 1 : HeLa whole cell lysate
Lane 2 : HepG2 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 38 kDa
10% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded HeLa xenograft tissue labeling HOXC10 with ab153904 at 1/500 dilution.
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Anti-HOXC10 antibody (ab153904) at 1/1000 dilution + Mouse muscle lysate at 50 µg
Predicted band size: 38 kDa
10% SDS PAGE
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (19)
ab153904 has been referenced in 19 publications.
- Xi Y et al. Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma. Signal Transduct Target Ther 7:53 (2022). PubMed: 35210398
- Wu K et al. MiR-4739 inhibits the malignant behavior of esophageal squamous cell carcinoma cells via the homeobox C10/vascular endothelial growth factor A/phosphatidylinositol 3-kinase/AKT pathway. Bioengineered 13:14066-14079 (2022). PubMed: 35730500
- Yu J et al. HOXC10 Promotes Metastasis in Colorectal Cancer by Recruiting Myeloid-derived Suppressor Cells. J Cancer 13:3308-3317 (2022). PubMed: 36186898
- Lin ZH et al. HOXC10 indicates poor survival outcome in gastric cancer and promotes G1/S cell cycle transition through transcriptional repression of p21. Neoplasma 69:1303-1313 (2022). PubMed: 36264773
- Xie Y et al. Transcription factor HOXC10 activates the expression of MTFR2 to regulate the proliferation, invasion and migration of colorectal cancer cells. Mol Med Rep 24:N/A (2021). PubMed: 34523692