Overview

  • Product nameAnti-Homocysteine antibody
    See all Homocysteine primary antibodies
  • Description
    Rabbit polyclonal to Homocysteine
  • SpecificityUsing conjugated Homocysteine-Glutaraldehyde-Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds:Compound : Cross-reactivity ratio(a) Cysteine-G-BSA: 1/423 Homocysteic acid-G-BSA: 1/>100000 (a) Homocysteine-G-BSA concentration/unconjugated or conjugated amino acids concentration at half displacement G = Glutaraldehyde, BSA = Bovine Serum Albumin
  • Tested applicationsSuitable for: ELISAmore details
  • Immunogen

    Chemical/ Small Molecule by a Glutaraldehyde linker.

Properties

Applications

Our Abpromise guarantee covers the use of ab6482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesFor ELISA, dilute 1:2000 - 1:10000 in PBS.
    Optimal dilutions should be determined by the individual
  • Target

    • RelevanceHomocysteine is a chemical compound with the formula HSCH2CH2CH(NH2)CO2H. It is a homologue of the naturally-occurring amino acid cysteine, differing in that its side-chain contains an additional methylene (-CH2-) group before the thiol (-SH) group. Alternatively, Homocysteine can be derived from methionine by removing the latter's terminal C methyl group. Elevations of Homocysteine also occur in the rare hereditary disease homocystinuria and in methylene-tetrahydrofolate-reductase deficiency. The latter is quite common and usually goes unnoticed, although there are reports that thrombosis and cardiovascular disease occurs more often in people with elevated Homocysteine.
    • Alternative names
      • (2S) 2 amino 4 sulfanyl butanoic acid antibody

    References for Anti-Homocysteine antibody (ab6482)

    This product has been referenced in:
    • Ganapathy PS  et al. Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse. Invest Ophthalmol Vis Sci 50:4460-70 (2009). Read more (PubMed: 19357353) »

    See 1 Publication for this product

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    The originator of ab6482 was only able to tell me that when ab6482 was tested in ELISA, conjugated homocysteine was used and not free homocysteine. Unfortunately I cannot provide you with any more information at this time.

    Thank you for your enquiry. All the information that we have at this time is located on the online datasheet. The antibody was tested in ELISA using conjugated Homocysteine-Glutaraldehyde-Protein.

    1. We estimate the molecular weight of this antibody to be between 150-160 kDa and the concentration to be around 1mg/ml.
    2. The epitope has not been mapped
    3. We have not tested stability in ascorbic acid
    We suggest that the antibody...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"