Overview

  • Product nameAnti-HOOK1 antibody
    See all HOOK1 primary antibodies
  • Description
    Rabbit polyclonal to HOOK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-728 of Human HOOK1 (NP_056972.1).

  • Positive control
    • Human pancreas and Mouse testis tissue lysates; HOOK1 transfected 293T cell line lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab103533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 85 kDa.

Target

  • FunctionRequired for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
  • Sequence similaritiesBelongs to the hook family.
  • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm. Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • A930033L17Rik antibody
    • Abnormal spermatozoon head shape antibody
    • azh antibody
    • h-hook1 antibody
    • hHK1 antibody
    • HK1 antibody
    • HOOK 1 antibody
    • Hook homolog 1 (Drosophila) antibody
    • Hook1 antibody
    • HOOK1_HUMAN antibody
    • MGC10642 antibody
    • OTTHUMP00000010548 antibody
    • OTTMUSP00000008480 antibody
    • Protein Hook homolog 1 antibody
    • RP23-80B16.4 antibody
    see all

Anti-HOOK1 antibody images

  • Anti-HOOK1 antibody (ab103533) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

    Predicted band size : 85 kDa
  • Anti-HOOK1 antibody (ab103533) at 1/500 dilution + Mouse testis tissue lysate at 50 µg

    Predicted band size : 85 kDa
  • All lanes : Anti-HOOK1 antibody (ab103533) at 1/500 dilution

    Lane 1 : HOOK1 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 85 kDa

References for Anti-HOOK1 antibody (ab103533)

ab103533 has not yet been referenced specifically in any publications.

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