Overview

  • Product nameAnti-HOOK1 antibody
    See all HOOK1 primary antibodies
  • Description
    Rabbit polyclonal to HOOK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 464-513 (REVFIRLQHE NKMLRLQQEG SENERIEELQ EQLEQKHRKM NELETEQRLS) of Human HOOK1 (NP_056972).

  • Positive control
    • Human fetal heart lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 85 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
  • Sequence similaritiesBelongs to the hook family.
  • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm. Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • A930033L17Rik antibody
    • Abnormal spermatozoon head shape antibody
    • azh antibody
    • h-hook1 antibody
    • hHK1 antibody
    • HK1 antibody
    • HOOK 1 antibody
    • Hook homolog 1 (Drosophila) antibody
    • Hook1 antibody
    • HOOK1_HUMAN antibody
    • MGC10642 antibody
    • OTTHUMP00000010548 antibody
    • OTTMUSP00000008480 antibody
    • Protein Hook homolog 1 antibody
    • RP23-80B16.4 antibody
    see all

Anti-HOOK1 antibody images

  • Anti-HOOK1 antibody (ab122997) at 1 µg/ml + Human fetal heart lysate at 10 µg

    Predicted band size : 85 kDa

References for Anti-HOOK1 antibody (ab122997)

ab122997 has not yet been referenced specifically in any publications.

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