Overview

  • Product nameAnti-HOOK2 antibody
    See all HOOK2 primary antibodies
  • Description
    Mouse monoclonal to HOOK2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: LEESVQHVVM EAIQELMTKD TPDSLSPETY GNFDSQSRRY YFLSEEAEEG DELQQRCLDL ERQLMLLSEE KQSLAQENAG LRERMGRPEG EGTPGLTAKK , corresponding to amino acids 138-238 of Human HOOK2

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab57108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceHOOK2 is a member of the Hook protein family. Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK2 localizes to the centrosome through all phases of the cell cycle. Interference with HOOK2 function results in the loss of the radial organization of microtubules suggesting that HOOK2 contributes to the establishment and maintenance of centrosomal structure and function. HOOK2 may contribute to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes.
    • Cellular localizationCytoplasmic. Note=Associates with discrete punctate structure that correspond to neither early or late endosomes, lysosomes, multivesicular bodies (MVBs), Golgi complex, endoplasmic reticulum, nor mitochondria.
    • Database links
    • Alternative names
      • A630054I03Rik antibody
      • FLJ26218 antibody
      • h hook2 antibody
      • hHK 2 antibody
      • hHK2 antibody
      • hhook 2 antibody
      • hhook2 antibody
      • HK 2 antibody
      • HK2 antibody
      • HOOK 2 antibody
      • hook homolog 2 (Drosophila) antibody
      • Hook homolog 2 antibody
      • MGC28586 antibody
      • MGC91008 antibody
      see all

    Anti-HOOK2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57108 HOOK2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-HOOK2 antibody (ab57108)

    ab57108 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57108.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"