Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab213567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 34 kDa.

Target

  • Function
    Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
  • Involvement in disease
    Note=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch) antibody
    • Homeo box 11 (T cell lymphoma 3 associated breakpoint) antibody
    • Homeobox 11 antibody
    • Homeobox protein Hox 11 antibody
    • Homeobox protein Hox-11 antibody
    • Homeobox TLX-1 antibody
    • Hox-11 antibody
    • Hox11 antibody
    • MGC163402 antibody
    • OTTHUMP00000020816 antibody
    • Proto oncogene TCL 3 antibody
    • Proto-oncogene TCL-3 antibody
    • RGD1563655 antibody
    • T cell leukemia homeobox protein 1 antibody
    • T cell leukemia lymphoma protein 3 antibody
    • T-all, included antibody
    • T-cell acute lymphocytic leukemia, included antibody
    • T-cell leukemia 3 gene antibody
    • T-cell leukemia homeobox protein 1 antibody
    • T-cell leukemia, homeobox 1 antibody
    • T-cell leukemia/lymphoma protein 3 antibody
    • TCL 3 proto oncogene antibody
    • TCL3 antibody
    • Tlx-1 antibody
    • TLX1 antibody
    • TLX1_HUMAN antibody
    see all

Images

  • Lanes 1 - 2 : Anti-HOX11 antibody (ab213567) at 1/500 dilution
    Lane 3 : Anti-HOX11 antibody (ab213567) at 1/1000 dilution

    Lane 1 : Lysate of HEK-293T cells overexpressing Human HOX11
    Lane 2 : Lysate of HEK-293T cells overexpressing Human HOX11 with HOX11 immunizing peptide (human, 176-188)
    Lane 3 : Lysate of HEK-293T cells overexpressing Human HOX11

    Secondary
    Goat Anti-Rabbit IgG-Peroxidase
    Developed using the ECL technique

    Predicted band size : 34 kDa

References

ab213567 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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