Overview

  • Product name
  • Description
    Rabbit polyclonal to HOX11
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to a portion of the amino acids 300-330 of Human HOX11

  • Positive control
    • Thymus tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab78498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notes
    IHC-P: Use at a concentration of 5 µg/ml.
    WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 34 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
    • Involvement in disease
      Note=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.
    • Sequence similarities
      Contains 1 homeobox DNA-binding domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch) antibody
      • Homeo box 11 (T cell lymphoma 3 associated breakpoint) antibody
      • Homeobox 11 antibody
      • Homeobox protein Hox 11 antibody
      • Homeobox protein Hox-11 antibody
      • Homeobox TLX-1 antibody
      • Hox-11 antibody
      • Hox11 antibody
      • MGC163402 antibody
      • OTTHUMP00000020816 antibody
      • Proto oncogene TCL 3 antibody
      • Proto-oncogene TCL-3 antibody
      • RGD1563655 antibody
      • T cell leukemia homeobox protein 1 antibody
      • T cell leukemia lymphoma protein 3 antibody
      • T-all, included antibody
      • T-cell acute lymphocytic leukemia, included antibody
      • T-cell leukemia 3 gene antibody
      • T-cell leukemia homeobox protein 1 antibody
      • T-cell leukemia, homeobox 1 antibody
      • T-cell leukemia/lymphoma protein 3 antibody
      • TCL 3 proto oncogene antibody
      • TCL3 antibody
      • Tlx-1 antibody
      • TLX1 antibody
      • TLX1_HUMAN antibody
      see all

    Images

    • ab78498, at 5µg/ml, staining HOX11 in thymus tissue.

    References

    This product has been referenced in:
    • Novakovic B  et al. Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation. Sci Rep 7:4523 (2017). Read more (PubMed: 28674422) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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