Overview

  • Product nameAnti-HOX11 antibody
    See all HOX11 primary antibodies
  • Description
    Rabbit polyclonal to HOX11
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 144 - 193 (VAHPQPLATG LPTVPSVPAM PGVNNLTGLT FPWMESNRRY TKDRFTGHPY) of human HOX11 (NP_005512).

  • Positive control
    • Fetal heart lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab83059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay, 1:312500.

Target

  • FunctionControls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
  • Involvement in diseaseNote=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD.
  • Sequence similaritiesContains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homeo box 11 (T cell leukemia 3 associated breakpoint homologous to Drosophila Notch) antibody
    • Homeo box 11 (T cell lymphoma 3 associated breakpoint) antibody
    • Homeobox 11 antibody
    • Homeobox protein Hox 11 antibody
    • Homeobox protein Hox-11 antibody
    • Homeobox TLX-1 antibody
    • Hox-11 antibody
    • Hox11 antibody
    • MGC163402 antibody
    • OTTHUMP00000020816 antibody
    • Proto oncogene TCL 3 antibody
    • Proto-oncogene TCL-3 antibody
    • RGD1563655 antibody
    • T cell leukemia homeobox protein 1 antibody
    • T cell leukemia lymphoma protein 3 antibody
    • T-all, included antibody
    • T-cell acute lymphocytic leukemia, included antibody
    • T-cell leukemia 3 gene antibody
    • T-cell leukemia homeobox protein 1 antibody
    • T-cell leukemia, homeobox 1 antibody
    • T-cell leukemia/lymphoma protein 3 antibody
    • TCL 3 proto oncogene antibody
    • TCL3 antibody
    • Tlx-1 antibody
    • TLX1 antibody
    • TLX1_HUMAN antibody
    see all

Anti-HOX11 antibody images

  • Anti-HOX11 antibody (ab83059) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 34 kDa
    Observed band size : 34 kDa

References for Anti-HOX11 antibody (ab83059)

ab83059 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"