The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FunctionSequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments.
Involvement in diseaseAthabaskan brainstem dysgenesis syndrome Bosley-Salih-Alorainy syndrome
Sequence similaritiesBelongs to the Antp homeobox family. Labial subfamily. Contains 1 homeobox DNA-binding domain.