Overview

  • Product nameAnti-HOXA2 antibody
    See all HOXA2 primary antibodies
  • Description
    Rabbit polyclonal to HOXA2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 220-269 (SEKVEEDEEE KTLFEQALSV SGALLEREGY TFQQNALSQQ QAPNGHNGDS) of Human HOXA2 (NP_006726).

  • Positive control
    • ACHN cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab119126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • Involvement in diseaseDefects in HOXA2 are a cause of microtia hearing impairment and cleft palate (MHICP) [MIM:612290]. Microtia is a congenital deformity of the outer ear and occurs in approximately one in 8'000-10'000 births. It is characterized by a small, abnormally shaped outer ear. It can be unilateral or bilateral. Syndromic forms of microtia occur in conjunction with other abnormalities. The most common associated malformations is the cleft palate, a congenital fissure of the soft and/or hard palate due to faulty fusion. Defects in HOXA2 are a cause of autosomal-recessive bilateral microtia, mixed symmetrical severe to profound hearing impairment and partial cleft palate.
  • Sequence similaritiesBelongs to the Antp homeobox family. Proboscipedia subfamily.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI324701 antibody
    • homeo box A2 antibody
    • homeobox A2 antibody
    • Homeobox protein Hox-1K antibody
    • Homeobox protein Hox-A2 antibody
    • Hox-1.11 antibody
    • HOX1.11 antibody
    • HOX1K antibody
    • Hoxa-2 antibody
    • Hoxa11 antibody
    • HOXA2 antibody
    • HXA2_HUMAN antibody
    • MGC151482 antibody
    • MGC151484 antibody
    • RATHOX111A antibody
    see all

Anti-HOXA2 antibody images

  • Anti-HOXA2 antibody (ab119126) at 1 µg + ACHN cell lysate at 10 µg

    Predicted band size : 41 kDa

References for Anti-HOXA2 antibody (ab119126)

ab119126 has not yet been referenced specifically in any publications.

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