Overview

  • Product name
  • Description
    Goat polyclonal to HOXA9
  • Host species
    Goat
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Cow, Human
  • Immunogen

    Synthetic peptide by a Cysteine residue linker, corresponding to internal sequence amino acids 37-50 of Human HOXA9 (NP_689952.1).

  • Positive control
    • Mouse and Rat Spinal Cord lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab169567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 30-33 kDa (predicted molecular weight: 30 kDa).

Target

  • Function
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • Involvement in disease
    Note=A chromosomal aberration involving HOXA9 is found in a form of acute myeloid leukemia. Translocation t(7;11)(p15;p15) with NUP98.
    Note=A chromosomal aberration involving HOXA9 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with MSI2.
  • Sequence similarities
    Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Form
    HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells.
  • Alternative names
    • ABD-B antibody
    • Abd-B, drosophila, homolog of antibody
    • D6a9 antibody
    • Homeobox 1G antibody
    • Homeobox A9 antibody
    • Homeobox protein Hox-1.7 antibody
    • Homeobox protein Hox-1G antibody
    • Homeobox protein Hox-A9 antibody
    • Homeodomain protein HOXA9 antibody
    • Hox-1.7 antibody
    • Hox-1.7, mouse, homolog of antibody
    • HOX1 antibody
    • Hox1.7 antibody
    • Hox1G antibody
    • Hox1r5 antibody
    • Hoxa-9 antibody
    • Hoxa7 antibody
    • HOXA9 antibody
    • HOXA9/MSI2 fusion gene, included antibody
    • HOXA9/NUP98 fusion gene, included antibody
    • HXA9_HUMAN antibody
    • MGC1934 antibody
    see all

References

ab169567 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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