Overview

  • Product name
  • Description
    Rabbit polyclonal to HOXD10
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Mouse HOXD10 aa 200-230 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P28359

  • Positive control
    • Mouse uterus tissue and NCI-H292 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab172865 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab172865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 38 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • Tissue specificity
    Strongly expressed in the adult male and female urogenital tracts.
  • Involvement in disease
    Defects in HOXD10 are a cause of congenital vertical talus (CVT) [MIM:192950]; also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity.
  • Sequence similarities
    Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Developmental stage
    Expressed in the developing limb buds.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI385591 antibody
    • AI874987 antibody
    • Homeo box 4D antibody
    • Homeo box D10 antibody
    • Homeobox D10 antibody
    • Homeobox protein Hox-4D antibody
    • Homeobox protein Hox-4E antibody
    • Homeobox protein Hox-D10 antibody
    • Hox 4.4 antibody
    • Hox 4.5 antibody
    • Hox 4D antibody
    • Hox 4E antibody
    • Hox 5.3 antibody
    • HOX4D antibody
    • HOX4E antibody
    • HOXD10 antibody
    • HXD10 antibody
    • HXD10_HUMAN antibody
    • OTTMUSP00000017845 antibody
    • RP23-313J15.9 antibody
    see all

Images

  • Anti-HOXD10 antibody (ab172865) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

    Predicted band size: 38 kDa

  • Immunohistochemistry analysis of formalin-fixed paraffin-embedded Mouse uterus tissue labeling HOXD10 with ab172865 at 1/10 followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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