Overview

  • Product nameAnti-HP1 gamma antibody
    See all HP1 gamma primary antibodies
  • Description
    Rabbit polyclonal to HP1 gamma
  • Tested applicationsSuitable for: WB, ICC/IF, ChIPmore details
  • Species reactivity
    Reacts with: Hamster, Human
    Predicted to work with: Mouse, Chicken, Xenopus laevis, Drosophila melanogaster, Zebrafish, Xenopus tropicalis
  • Immunogen

    Synthetic peptide corresponding to Human HP1 gamma aa 174-183 (C terminal).
    Sequence:

    WHSCPEDEAQ-C


    Database link: Q13185

  • Positive control
    • MCF7 cell extract

Properties

Applications

Our Abpromise guarantee covers the use of ab122974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 20 kDa.
ICC/IF Use at an assay dependent concentration.
ChIP Use at an assay dependent concentration.

Target

  • FunctionSeems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
  • Sequence similaritiesContains 2 chromo domains.
  • Post-translational
    modifications
    Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.
  • Cellular localizationNucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • CBX 3 antibody
    • CBX3 antibody
    • CBX3_HUMAN antibody
    • Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody
    • Chromobox homolog 3 antibody
    • Chromobox protein homolog 3 antibody
    • GAMMA antibody
    • HECH antibody
    • Heterochromatin like protein 1 antibody
    • Heterochromatin protein 1 homolog gamma antibody
    • Heterochromatin protein HP1 gamma antibody
    • HP1 gamma antibody
    • HP1 gamma homolog antibody
    • HP1Hs gamma antibody
    • Modifier 2 protein antibody
    see all

Anti-HP1 gamma antibody images

  • Anti-HP1 gamma antibody (ab122974) at 1/2000 dilution + Baby Hamster Kidney cells

    Predicted band size : 20 kDa

References for Anti-HP1 gamma antibody (ab122974)

ab122974 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"