• Product nameAnti-HP1 gamma antibody
    See all HP1 gamma primary antibodies
  • Description
    Rabbit polyclonal to HP1 gamma
  • Tested applicationsSuitable for: IP, IHC-Pmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis , Medaka fish
  • Immunogen

    Synthetic peptide corresponding to a region between residue 133 and the C-terminus (residue 183) of human HP1 gamma (NP_009207.2)

  • Positive control
    • HeLa whole cell lysate.


Associated products


Our Abpromise guarantee covers the use of ab72043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
IHC-P 1/2000 - 1/10000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionSeems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
    • Sequence similaritiesContains 2 chromo domains.
    • Post-translational
      Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.
    • Cellular localizationNucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.
    • Information by UniProt
    • Database links
    • Alternative names
      • CBX 3 antibody
      • CBX3 antibody
      • CBX3_HUMAN antibody
      • Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody
      • Chromobox homolog 3 antibody
      • Chromobox protein homolog 3 antibody
      • GAMMA antibody
      • HECH antibody
      • Heterochromatin like protein 1 antibody
      • Heterochromatin protein 1 homolog gamma antibody
      • Heterochromatin protein HP1 gamma antibody
      • HP1 gamma antibody
      • HP1 gamma homolog antibody
      • HP1Hs gamma antibody
      • Modifier 2 protein antibody
      see all

    Anti-HP1 gamma antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma (left) and mouse teratoma (right) tissues labelling HP1 gamma with ab72043 at 1/5000 (0.2µg/ml). Detection: DAB.
    • Detection of HP1 gamma by Western Blot of Immunprecipitate.
      anti-HP1 gamma (ab72042) at 1µg/ml staining HP1 gamma in HeLa whole cell lysate immunoprecipitated using ab72043 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 30 seconds.

    References for Anti-HP1 gamma antibody (ab72043)

    ab72043 has not yet been referenced specifically in any publications.

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