Overview

  • Product nameAnti-HPD antibody [EPR5296]
    See all HPD primary antibodies
  • Description
    Rabbit monoclonal [EPR5296] to HPD
  • SpecificityBased on the immunogen sequence, ab108506 does not recognize Isoform 2 of human HPD.
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human HPD

  • Positive control
    • HepG2 and fetal liver lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5, 675, 063 and/or 7, 429, 487.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab108506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionKey enzyme in the degradation of tyrosine.
    • PathwayAmino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.
    • Involvement in diseaseTyrosinemia 3
      Hawkinsinuria
    • Sequence similaritiesBelongs to the 4HPPD family.
    • Information by UniProt
    • Database links
    • Alternative names
      • 4 HPPD antibody
      • 4 hydroxyphenylpyruvate dioxygenase antibody
      • 4 hydroxyphenylpyruvic acid oxidase antibody
      • 4-hydroxyphenylpyruvate dioxygenase antibody
      • 4-hydroxyphenylpyruvic acid oxidase antibody
      • 4HPPD antibody
      • GLOD3 antibody
      • glyoxalase domain containing 3 antibody
      • HPD antibody
      • HPPD_HUMAN antibody
      • HPPDase antibody
      • PPD antibody
      see all

    Anti-HPD antibody [EPR5296] images

    • All lanes : Anti-HPD antibody [EPR5296] (ab108506) at 1/1000 dilution

      Lane 1 : HepG2 lysate.
      Lane 2 : Fetal liver lysate.

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 45 kDa
      Observed band size : 45 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-HPD antibody [EPR5296] (ab108506)

    ab108506 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108506.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"