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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 114 kDa.
1/100 - 1/500.
HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
Anti-HPS3 antibody images
Western blot - HPS3 antibody (ab96343)
All lanes : Anti-HPS3 antibody (ab96343) at 1/1000 dilution Lane 1 : 293T whole cell lysate Lane 2 : A431 whole cell lysate Lane 3 : H1299 whole cell lysate Lane 4 : HeLa S3 whole cell lysate Lane 5 : HepG2 whole cell lysate Lane 6 : MOLT4 whole cell lysate Lane 7 : Raji whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 114 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HPS3 antibody (ab96343)
ab96343, at 1/500 dilution, staining HPS3 in paraffin-embedded SW480 by Immunohistochemistry.
References for Anti-HPS3 antibody (ab96343)
has not yet been referenced specifically in any publications.
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