Overview

  • Product name
    Anti-HPV18 E6 antibody [BF7]
  • Description
    Mouse monoclonal [BF7] to HPV18 E6
  • Tested applications
    Suitable for: WB, RIA, ELISAmore details
  • Immunogen

    Gel-purified HPV-18 E6-beta-galactosidase fusion protein

Properties

Applications

Our Abpromise guarantee covers the use of ab20192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 17 kDa.
RIA Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • Relevance
    The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
  • Alternative names
    • E6 antibody
    • Human papillomavirus type 18 E6 antibody
    • Protein E6 antibody

References

This product has been referenced in:
  • Cheng Y  et al. Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2. Mol Med Rep 16:5464-5470 (2017). Read more (PubMed: 28849054) »
  • Banks L  et al. Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas. J Gen Virol 68 ( Pt 5):1351-9 (1987). Read more (PubMed: 3033140) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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