Overview

  • Product name
  • Description
    Goat polyclonal to HRASLS3
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide:

    RAPIPEPKPGDLIE-C

    , corresponding to N terminal amino acids 2-15 of Human HRASLS3 (NP_009000.2).

  • Positive control
    • Human Brain Cortex tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/128000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
  • Tissue specificity
    Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down-regulated in some ovarian carcinomas and testicular germ cell tumors.
  • Sequence similarities
    Belongs to the H-rev107 family.
  • Cellular localization
    Cytoplasm. Cytoplasm > perinuclear region. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adipose specific phospholipase A2 antibody
    • Adipose specific PLA2 antibody
    • Adipose-specific phospholipase A2 antibody
    • AdPLA antibody
    • Ca independent phospholipase A1/2 antibody
    • Group XVI phospholipase A1/A2 antibody
    • Group XVI phospholipase A2 antibody
    • H rev 107 protein homolog antibody
    • H REV107 1 antibody
    • H-rev 107 protein homolog antibody
    • HRAS like suppressor 1 antibody
    • HRAS like suppressor 3 antibody
    • HRAS-like suppressor 1 antibody
    • HRAS-like suppressor 3 antibody
    • HREV107 1 antibody
    • HREV107 3 antibody
    • HREV107 antibody
    • HREV107-1 antibody
    • HREV107-3 antibody
    • HRSL3 antibody
    • HRSL3_HUMAN antibody
    • Phospholipase A2 group XVI antibody
    • Pla2g16 antibody
    • Renal carcinoma antigen NY REN 65 antibody
    • Renal carcinoma antigen NY-REN-65 antibody
    see all

Images

  • ab104454, at 5 µg/ml, staining HRASLS3 in formalin-fixed, paraffin-embedded Human Brain Cortex by Immunohistochemistry, followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab104454 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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