Anti-HRG antibody - N-terminal (ab85209)

Overview

  • Product nameAnti-HRG antibody - N-terminal
    See all HRG primary antibodies
  • Description
    Rabbit polyclonal to HRG - N-terminal
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH-conjugated synthetic peptide designed within the N-terminal region of Human HRG

  • Positive control
    • K562 cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityAmmonium Sulphate Precipitation
  • Purification notesPrepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab85209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 60 kDa.
ELISA 1/1000.

Target

  • RelevanceHRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • DKFZp779H1622 antibody
    • Histidine proline rich glycoprotein antibody
    • Histidine rich glycoprotein antibody
    • HPRG antibody
    • HRGP antibody
    • Thrombophilia due to elevated HRG antibody
    see all

Anti-HRG antibody - N-terminal images

  • Anti-HRG antibody - N-terminal (ab85209) at 1/50 dilution + K562 cell lysate at 35 µg

    Predicted band size : 60 kDa
    Observed band size : 60 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

References for Anti-HRG antibody - N-terminal (ab85209)

ab85209 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"