Anti-HRG antibody [RM0091-9G42] (ab86451)

Overview

  • Product name
    Anti-HRG antibody [RM0091-9G42]
    See all HRG primary antibodies
  • Description
    Rat monoclonal [RM0091-9G42] to HRG
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant HRG protein (Mouse)

  • General notes


    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from an 0.2 µm filtered solution.
  • Primary antibody notes
    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
  • Clonality
    Monoclonal
  • Clone number
    RM0091-9G42
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 60 kDa.

Target

  • Relevance
    HRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • DKFZp779H1622 antibody
    • Histidine proline rich glycoprotein antibody
    • Histidine rich glycoprotein antibody
    • HPRG antibody
    • HRGP antibody
    • Thrombophilia due to elevated HRG antibody
    see all

References for Anti-HRG antibody [RM0091-9G42] (ab86451)

ab86451 has not yet been referenced specifically in any publications.

Product Wall

The Anti-HRG antibody [RM0091-9G42] (ab86451) has been raised against the full length recombinant mouse HRG protein. Unfortunately the specific epitope recognised by the antibody produced from this clone has not as yet been determined.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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