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Rabbit polyclonal to HRH1
Recombinant fragment, corresponding to a region within amino acids 70-323 of Human HRH1.
293T, A431, HeLa, HepG2 whole cell lysates; Cal27 xenograft.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 56 kDa.
1/100 - 1/1000.
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Belongs to the G-protein coupled receptor 1 family.
Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
Information by UniProt
BPHS, mouse, homolog of antibody
H1 R antibody
Western blot - Anti-HRH1 antibody (ab154158)
All lanes : Anti-HRH1 antibody (ab154158) at 1/1000 dilution Lane 1 : 293T whole cell lysate Lane 2 : A431 whole cell lysate Lane 3 : HeLa whole cell lysate Lane 4 : HepG2 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 56 kDa 7.5% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HRH1 antibody (ab154158)
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft tissue labeling HRH1 with ab154158 at 1/500 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"