Overview

  • Product name
  • Description
    Goat polyclonal to HRH1
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Gorilla, Orangutan
  • Immunogen

    Synthetic peptide:

    QQTSVRREDKCETD

    , corresponding to internal sequence amino acids 170-183 of human HRH1 (NP_000852.1)

  • Positive control
    • Human heart lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab77100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 56 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 2 - 4 µg/ml.

Target

  • Function
    In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPHS, mouse, homolog of antibody
    • H1 R antibody
    • H1R antibody
    • HH1R antibody
    • HisH1 antibody
    • Histamine H(1) receptor antibody
    • Histamine H1 receptor antibody
    • Histamine receptor H1 antibody
    • Histamine receptor subclass H1 antibody
    • Hrh1 antibody
    • HRH1_HUMAN antibody
    see all

Anti-HRH1 antibody images

  • Immunohistochemistry (paraffin-embedded sections) analysis of human lung tissue labeling HRH1 with ab77100 at 4µg/ml. Microwaved antigen retrieval was performed using Tris/EDTA buffer pH 6. HRP staining.

  • Anti-HRH1 antibody (ab77100) at 0.5 µg/ml + Heart lysate (in RIPA buffer) at 35 µg

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

References for Anti-HRH1 antibody (ab77100)

ab77100 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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