Overview

  • Product name
  • Description
    Goat polyclonal to HRH2
  • Specificity
    ab118279 is expected to recognize both reported isoforms (NP_001124527.1; NP_071640.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    SHNSHKTSLRLNNS

    with a Cysteine residue linker, corresponding to internal sequence amino acids 309-322 of Human HRH2 (NP_001124527.1; NP_071640.1).

  • Positive control
    • Human Duodenum and Ileum lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab118279 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

Target

  • Function
    The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Gastric receptor 1 antibody
    • Gastric receptor I antibody
    • H2R antibody
    • HGNC:5183 antibody
    • HH2R antibody
    • Histamine H2 receptor antibody
    • Histamine receptor H2 antibody
    • HRH2 antibody
    • HRH2_HUMAN antibody
    • OTTHUMP00000161242 antibody
    • OTTHUMP00000161243 antibody
    see all

Images

  • Anti-HRH2 antibody (ab118279) at 0.1 µg/ml + Human Duodenum lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 45 kDa
    Observed band size : 45 kDa


    Exposure time : 1 hour

References

ab118279 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab118279.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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