Overview

  • Product nameAnti-HRH2 antibody [EPR5630]
    See all HRH2 primary antibodies
  • Description
    Rabbit monoclonal [EPR5630] to HRH2
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to a region in Human HRH2.

  • Positive control
    • Human fetal brain, adrenal gland and SH-SY5Y cell line lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab108540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 40 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionThe H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Gastric receptor 1 antibody
      • Gastric receptor I antibody
      • H2R antibody
      • HGNC:5183 antibody
      • HH2R antibody
      • Histamine H2 receptor antibody
      • Histamine receptor H2 antibody
      • HRH2 antibody
      • HRH2_HUMAN antibody
      • OTTHUMP00000161242 antibody
      • OTTHUMP00000161243 antibody
      see all

    Anti-HRH2 antibody [EPR5630] images

    • All lanes : Anti-HRH2 antibody [EPR5630] (ab108540) at 1/10000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : Human adrenal gland lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 40 kDa

    References for Anti-HRH2 antibody [EPR5630] (ab108540)

    ab108540 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108540.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"