HRH2 peptide (335-349) (Carboxyterminal end) (ab45807)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-QEEKPLKLQVWSGTE
    • Amino acids335 to 349

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-HRH2 antibody (ab39964)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • Gastric receptor 1
    • Gastric receptor I
    • H2R
    • HGNC:5183
    • HH2R
    • Histamine H2 receptor
    • Histamine receptor H2
    • HRH2
    • HRH2_HUMAN
    • OTTHUMP00000161242
    • OTTHUMP00000161243
    see all
  • FunctionThe H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for HRH2 peptide (335-349) (Carboxyterminal end) (ab45807)

ab45807 has not yet been referenced specifically in any publications.

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