Overview

  • Product name
  • Description
    Rabbit polyclonal to HRSP12
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-137 of Human HRSP12 (Uniprot ID: P52758).

  • Positive control
    • A549, HepG2 and HCT116 whole cell lysates; Human DLD1 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab151292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 14 kDa.
IHC-P 1/500 - 1/3000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
  • Tissue specificity
    Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues.
  • Sequence similarities
    Belongs to the RutC family.
  • Developmental stage
    Up-regulated during cellular differentiation.
  • Cellular localization
    Cytoplasm. Nucleus. Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • 14.5 kDa translational inhibitor protein antibody
    • 2-iminobutanoate/2-iminopropanoate deaminase antibody
    • Heat responsive protein 12 antibody
    • Heat-responsive protein 12 antibody
    • Hrsp12 antibody
    • p14.5 antibody
    • Perchloric acid soluble protein antibody
    • PSP antibody
    • Reactive intermediate imine deaminase A homolog antibody
    • Ribonuclease UK114 antibody
    • RIDA antibody
    • Translational inhibitor p14.5 antibody
    • Translational inhibitor protein p14.5 antibody
    • UK114 antibody
    • UK114 antigen homolog antibody
    • UK114_HUMAN antibody
    see all

Images

  • Anti-HRSP12 antibody (ab151292) at 1/2000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size: 14 kDa



    15% SDS PAGE.
  • Immunohistochemical analysis of paraffin-embedded Human DLD1 xenograft tissue labeling HRSP12 with ab151292 at 1/500 dilution.

References

ab151292 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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