Overview

  • Product name
  • Description
    Rabbit polyclonal to HS3ST5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 280-329 (SQYNLYFNAT RGFYCLRFNI IFNKCLAGSK GRIHPEVDPS VITKLRKFFH) of Human HS3ST5 (NP_705840).

  • Positive control
    • MCF7 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Rate limiting enzyme for synthesis of HSact. Performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.
  • Tissue specificity
    Highly expressed in skeletal muscle and fetal brain, and also found in adult brain, spinal cord, cerebellum and colon.
  • Sequence similarities
    Belongs to the sulfotransferase 1 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-OST-5 antibody
    • 3OST5 antibody
    • h3-OST-5 antibody
    • Heparan sulfate (glucosamine) 3 O sulfotransferase 5 antibody
    • Heparan sulfate 3 OST 5 antibody
    • Heparan sulfate 3-O-sulfotransferase 5 antibody
    • Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5 antibody
    • Heparan sulfate glucosamine 3 sulfotransferase 5 antibody
    • Heparan sulfate glucosamine 3-O-sulfotransferase 5 antibody
    • HS3OST5 antibody
    • HS3S5_HUMAN antibody
    • HS3ST5 antibody
    • NBLA04021 antibody
    • Nbla04021 product like antibody
    see all

Images

  • Anti-HS3ST5 antibody (ab105776) at 0.5 µg/ml + MCF7 cell lysate at 10 µg

    Predicted band size : 40 kDa

References

ab105776 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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