Overview

  • Product nameAnti-HSC70 Interacting Protein HIP antibody
    See all HSC70 Interacting Protein HIP primary antibodies
  • Description
    Rabbit polyclonal to HSC70 Interacting Protein HIP
  • Tested applicationsSuitable for: IP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to human Interacting Protein HIP

  • Positive control
    • Colon cancer tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 1% BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab73917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration. PubMed: 21163940
WB Use at an assay dependent concentration. PubMed: 21163940
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionOne HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
  • Sequence similaritiesBelongs to the FAM10 family.
    Contains 1 STI1 domain.
    Contains 3 TPR repeats.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAG 2 antibody
    • AAG2 antibody
    • Aging associated protein 2 antibody
    • F10A1_HUMAN antibody
    • FAM10A1 antibody
    • FAM10A4 antibody
    • FLJ27260 antibody
    • Heat shock 70kD protein binding protein antibody
    • Hip antibody
    • HOP antibody
    • Hsc70 interacting protein antibody
    • Hsc70-interacting protein antibody
    • Hsp70 interacting protein antibody
    • HSPABP 1 antibody
    • HSPABP antibody
    • HSPABP1 antibody
    • MGC129952 antibody
    • OTTHUMP00000028873 antibody
    • P48 antibody
    • PRO0786 antibody
    • Progesterone receptor associated p48 protein antibody
    • Progesterone receptor-associated p48 protein antibody
    • Protein FAM10A1 antibody
    • Putative tumor suppressor ST13 antibody
    • Renal carcinoma antigen NY REN 33 antibody
    • Renal carcinoma antigen NY-REN-33 antibody
    • SNC 6 antibody
    • SNC6 antibody
    • ST 13 antibody
    • St13 antibody
    • Suppression of tumorigenicity 13 antibody
    • Suppression of tumorigenicity 13 (colon carcinoma) antibody
    • Suppression of tumorigenicity 13 protein antibody
    • Suppression of tumorigenicity protein 13 antibody
    see all

Anti-HSC70 Interacting Protein HIP antibody images

  • All lanes : Anti-HSC70 Interacting Protein HIP antibody (ab73917) at 1/250 dilution

    Lane 1 : Recombinant Human HSC70 Interacting Protein HIP (ab61296) at 0.1 µg
    Lane 2 : Recombinant Human HSC70 Interacting Protein HIP (ab61296) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 10 seconds

References for Anti-HSC70 Interacting Protein HIP antibody (ab73917)

This product has been referenced in:
  • Soler-López M  et al. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Res 21:364-76 (2011). WB, IP ; Human . Read more (PubMed: 21163940) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"