The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/3000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
FunctionOne HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Sequence similaritiesBelongs to the FAM10 family. Contains 1 STI1 domain. Contains 3 TPR repeats.