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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration information loading...
Purity Protein G purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 35 kDa).
Function Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
Tissue specificity Testis.
Pathway Hormone biosynthesis; testosterone biosynthesis.
Involvement in disease Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH) [MIM:264300]. These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place.
Sequence similarities Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
Information by UniProt
17 @beta HSD III antibody
17 beta HSD 3 antibody
17-@beta hydroxysteroid dehydrogenase III antibody
Anti-HSD17B3 antibody images
Western blot - HSD17B3 antibody (ab70089)
All lanes : Anti-HSD17B3 antibody (ab70089) at 1/500 dilution Lane 1 : HSD17B3 transfected 293T cell lysate Lane 2 : Non-transfected 293T cell lysate Lysates/proteins at 25 µg per lane. Secondary Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution Predicted band size : 35 kDa Observed band size : 30 kDa ( why is the actual band size different from the predicted?)
References for Anti-HSD17B3 antibody (ab70089)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"